QUINONE-BASED THERAPEUTIC AGENT FOR HEPATIC DISEASE

PROBLEM TO BE SOLVED: To provide an excellent therapeutic agent for hepatic diseases due to the inhibition of the development of portal venous invasion (PVI). SOLUTION: The excellent therapeutic and prophylactic agent for hepatic diseases comprises menatetrenone as an active ingredient. The therapeu...

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Hauptverfasser: YOSHIDA HARUHIKO, TERATANI TAKUMA, SUGATA YOSHIO, AKAMATSU MASATOSHI, TATEISHI RYOSUKE, SHIRATORI YASUSHI, MIZUTA TOSHIHIKO, YAMAMOTO KYOSUKE, KAWASE TAKEO, FUJIMOTO MASARU, ISHIKAWA TAKASHI, SATO SHINPEI, KOO SHUNTARO, SHIINA SHIYUUICHIRO, HAMAMURA KEISUKE, FUJISHIMA TOMONORI, KOMATA MASAO, KOIKE YUKIHIRO, YASUTAKE TSUTOMU, OZAKI IWATA
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Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide an excellent therapeutic agent for hepatic diseases due to the inhibition of the development of portal venous invasion (PVI). SOLUTION: The excellent therapeutic and prophylactic agent for hepatic diseases comprises menatetrenone as an active ingredient. The therapeutic and prophylactic agent is especially effective for des-γ-carboxy prothrombin (DCP)-positive hepatic cancer. The therapeutic and prophylactic agent is an inhibitor of the development of the portal venous invasion (PVI) and has remarkable effects on amelioration for prognosis after treating hepatic cancer. Furthermore, the therapeutic and prophylactic agent has excellent effects even as an inhibitor of relapse of the hepatic caner. COPYRIGHT: (C)2004,JPO