LIQUID COMPOSITION FOR AEROSOL PREPARATION

PROBLEM TO BE SOLVED: To obtain a composition for an aerosol preparation free of irritancy to the throat and the nose and good in usability, specifically containing a sparingly water-soluble medicament such as indomethacin or ketoprofen, and to provide the aerosol preparation using the composition....

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1. Verfasser: SUGAFUJI HISAHIRO
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To obtain a composition for an aerosol preparation free of irritancy to the throat and the nose and good in usability, specifically containing a sparingly water-soluble medicament such as indomethacin or ketoprofen, and to provide the aerosol preparation using the composition. SOLUTION: The liquid composition comprises (A) the sparingly water-soluble medicament solid at 25°C under normal pressures, (B) 20-50 mass% of a polyhydric alcohol and/or an oily component, (C) 20-70 mass% of a ≤4C primary alcohol, and 0-20 mass% of water. The foamability of this composition is ≤10 mm determined by Ross Miles testing method( JIS K3362 ). COPYRIGHT: (C)2004,JPO