HYDROLYTIC STABILIZER AND PROMPTLY ADMINISTERING DEVICE

PROBLEM TO BE SOLVED: To form a quaternary pyridinium oxime and aldoxime into a storage- stable rapidly solvated organic inclusion complex. SOLUTION: The quaternary pyridinium oxime and aldoxime containing a carboxy, choline and a reactivator of other esterases are combined with a cyclodextrin to pr...

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Hauptverfasser: BHUPENDRA PANNALAL DOCTOR, JOSEPH MICHAEL MARASCO, BROWN NESBITT D
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To form a quaternary pyridinium oxime and aldoxime into a storage- stable rapidly solvated organic inclusion complex. SOLUTION: The quaternary pyridinium oxime and aldoxime containing a carboxy, choline and a reactivator of other esterases are combined with a cyclodextrin to provide the storage-stable rapidly solvated organic inclusion complex. The gun-type rapidly administering means including the organic inclusion complex so as to be freely dischargeable is also provided. As a result, the quaternary pyridinium and aldoxime effective for a mammal in the therapy of the neural toxicosis caused by the organophosphorus toxins can be formed into the stable form suitable for the storage. COPYRIGHT: (C)2003,JPO