MICROCAPSULE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a method for producing a sustained release microcapsule exhibiting sufficient sustained release property without using a thickening material, preventing the complication of the production of the raw materials and the process for the drug preparation and keeping high...

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Bibliographische Detailangaben
Hauptverfasser:	TAKEYAMA KEISUKE, SEKINO JUN, OKAZAKI JUNYA, OMURA TADAYOSHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method for producing a sustained release microcapsule exhibiting sufficient sustained release property without using a thickening material, preventing the complication of the production of the raw materials and the process for the drug preparation and keeping high content of the main drug in the capsule. SOLUTION: A W/O-type emulsion is produced by using a solution containing a water-soluble drug as the inner water phase and a solution containing a polymer as the oil phase. The emulsion is dispersed in an outer water phase to obtain a W/O/W-type emulsion and the product is dried in liquid to obtain the sustained release microcapsule of the water-soluble drug. A water-soluble metal salt compound is added to the water phase to be used at or after the preparation of the W/O/W-type emulsion. COPYRIGHT: (C)2003,JPO