SPECIFIC BINDING AGENT

PROBLEM TO BE SOLVED: To provide a specific binding agent for human polymorphic epithelial mucin. SOLUTION: This binding agent is a reshaped human antibody or reshaped human antibody fragment with a specificity to the human polymorphic epithelial muchin (PEM) including (i) at least one heavy-chain h...

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1. Verfasser: VERHOEYEN MARTINE ELISA
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creator VERHOEYEN MARTINE ELISA
description PROBLEM TO BE SOLVED: To provide a specific binding agent for human polymorphic epithelial mucin. SOLUTION: This binding agent is a reshaped human antibody or reshaped human antibody fragment with a specificity to the human polymorphic epithelial muchin (PEM) including (i) at least one heavy-chain having the same amino acid sequence as that in the heavy chain producible by means of the expression vector contained in Escherichia coli NCTC 12411 strain and (ii) at least one light-chain having the same amino acid sequence as that in the light-chain producible by means of the expression vector contained in Escherichia coli NCTC 12412 strain.
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SOLUTION: This binding agent is a reshaped human antibody or reshaped human antibody fragment with a specificity to the human polymorphic epithelial muchin (PEM) including (i) at least one heavy-chain having the same amino acid sequence as that in the heavy chain producible by means of the expression vector contained in Escherichia coli NCTC 12411 strain and (ii) at least one light-chain having the same amino acid sequence as that in the light-chain producible by means of the expression vector contained in Escherichia coli NCTC 12412 strain.</description><edition>7</edition><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20030304&amp;DB=EPODOC&amp;CC=JP&amp;NR=2003061689A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20030304&amp;DB=EPODOC&amp;CC=JP&amp;NR=2003061689A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VERHOEYEN MARTINE ELISA</creatorcontrib><title>SPECIFIC BINDING AGENT</title><description>PROBLEM TO BE SOLVED: To provide a specific binding agent for human polymorphic epithelial mucin. 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SOLUTION: This binding agent is a reshaped human antibody or reshaped human antibody fragment with a specificity to the human polymorphic epithelial muchin (PEM) including (i) at least one heavy-chain having the same amino acid sequence as that in the heavy chain producible by means of the expression vector contained in Escherichia coli NCTC 12411 strain and (ii) at least one light-chain having the same amino acid sequence as that in the light-chain producible by means of the expression vector contained in Escherichia coli NCTC 12412 strain.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title SPECIFIC BINDING AGENT
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