METHOD FOR NITRATION OF PHENOLIC COMPOUND

PROBLEM TO BE SOLVED: To provide a rational method for producing a nitrophenol compound, especially a 2,6-disubstituted-4-nitrophenol compound useful as an intermediate for pharmaceuticals in high yield. SOLUTION: The nitration is carried out by nitrosating a phenolic compound expressed by general formula (1) (R and R are each independently a lower alkyl, a lower alkenyl, an aralkyl or an aryl; and R and R are each independently H, a lower alkyl, a lower alkenyl, an aralkyl or an aryl) and oxidizing the produced nitroso group.