METHOD FOR GENE DIAGNOSIS OF BOVINE CLAUDIN-16 DEFICIENCY DISEASE TYPE 2

PROBLEM TO BE SOLVED: To provide a method for diagnosing bovine Claudin-16 deficiency disease type 2. SOLUTION: It was found that bovine Claudin-16 deficiency disease type 2 is caused by a DNA deficiency as large as about 56 kb including a part of Claudin-16 gene. The disease is gene diagnosed, for...

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Hauptverfasser:	KIKUCHI TAKUMI, INMAKI MISAO, HIRANO TAKASHI, HIRAI TOMOKAZU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method for diagnosing bovine Claudin-16 deficiency disease type 2. SOLUTION: It was found that bovine Claudin-16 deficiency disease type 2 is caused by a DNA deficiency as large as about 56 kb including a part of Claudin-16 gene. The disease is gene diagnosed, for example, by the presence or absence of the amplification of a region including the gene by using specific PCR primers depending on the deficiency. The diagnosis is carried out concretely by specifically amplifying a surrounding region of a gene of interest followed by detecting any deficiency. This method permits simply and rapidly detecting and diagnosing bovine Claudin-16 deficiency disease type 2 and a carrier thereof.