GRK INHIBITOR

GRK INHIBITOR

PROBLEM TO BE SOLVED: To obtain a new GRK inhibitor useful as a prophylactic or a therapeutic agent for cardiac insufficiency, etc. SOLUTION: This GRK inhibitor comprises a compound represented by the formula (I) [A denotes a nitrogen-containing heterocyclic ring which may further be substituted; R1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: IKEDA SHOTA, FUKUMOTO MASAJI, WATANABE TOSHIFUMI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To obtain a new GRK inhibitor useful as a prophylactic or a therapeutic agent for cardiac insufficiency, etc. SOLUTION: This GRK inhibitor comprises a compound represented by the formula (I) [A denotes a nitrogen-containing heterocyclic ring which may further be substituted; R1 and R2 denote each amino group which may respectively be substituted; X denotes a spacer in which the number of atoms constituting the straight-chain part is 1-4; and R1 may be bound to R2 or/and X to form a ring], or its salt or a prodrug thereof.