UROKINASE TYPE PLASMINOGEN ACTIVATING FACTOR RECEPTOR

PROBLEM TO BE SOLVED: To provide a method for detecting or quantitatively measuring a u-PAR in a biological sample collected from a biological system so as to examine or evaluate a function of the urokinase type plasminogen activator receptor (u-PAR) to a localized extracellular protease activity in...

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Hauptverfasser: APPELLA ETTORE, POELLAENEN JARI, PYKE CHARLES, BLASI FRANCESCO, MOELLER LISBETH BIRK, ELLIS VINCENT, ROLDAN ANN LOURING, SALONEN EEVA-MARJATTA, TAPIOVAARA HANNELE, SCHLEUNING W D, BEHRENDT NIELS, CUBELLIS MARIA VITTORIA, LUND LEIF ROEGE, PATTHY LASZLO, PLOUG MICHAEL, ROENNE EBBE, MASUCCI MARIA TERESA, STEPHENS ROSS W, DANOE KELD, KRISTENSEN PETER, VAHERI ANTTI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for detecting or quantitatively measuring a u-PAR in a biological sample collected from a biological system so as to examine or evaluate a function of the urokinase type plasminogen activator receptor (u-PAR) to a localized extracellular protease activity in the biological system. SOLUTION: An antibody monospecific to the u-PAR is bound to the u-PAR specifically, and the existence or the amount of the bound antibody is detected/ evaluated.