NEW BIPHENYL DERIVATIVE

NEW BIPHENYL DERIVATIVE

PROBLEM TO BE SOLVED: To provide a new biphenyl derivative effective as a steroid sulfatase inhibitor, for treating estrone diseases such as breast cancer, endometrial cancer, endometriosis or hysteromyoma. SOLUTION: This new biphenyl derivative is shown by the formula (I) [wherein, R is COOH, CONR1...

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Bibliographische Detailangaben
Hauptverfasser: MIYASAKA TOMOHIRO, INOUE YOSHIMASA, JINBO YOSHIKAZU
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a new biphenyl derivative effective as a steroid sulfatase inhibitor, for treating estrone diseases such as breast cancer, endometrial cancer, endometriosis or hysteromyoma. SOLUTION: This new biphenyl derivative is shown by the formula (I) [wherein, R is COOH, CONR1R2, CONR1OCH2C6H5, COR2 or C(OH)R1R2; R1 is H or a (substituted) alkyl; and R2 is a (substituted) alkyl].