MEDICINE FOR PERIODONTITIS

PROBLEM TO BE SOLVED: To obtain a prophylactic and a therapeutic agents for periodontitis safe for human bodies. SOLUTION: This medicine for the periodontitis comprises human β-defensin 1 or human β-defensin 2 or both which are safe human antimicrobial peptides produced by humans and is used to carr...

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Bibliographische Detailangaben
Hauptverfasser:	KOWASHI YUTEN, MIZOGUCHI ITARU, ARAKAWA TOSHIYA, KAKU TORU, NISHIMURA SATOKO, ABIKO YOSHIHIRO, NAKAJIMA KEISUKE, TAKUMA YASUNOBU
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To obtain a prophylactic and a therapeutic agents for periodontitis safe for human bodies. SOLUTION: This medicine for the periodontitis comprises human β-defensin 1 or human β-defensin 2 or both which are safe human antimicrobial peptides produced by humans and is used to carry out the prophylaxis and treatment of the periodontitis. Furthermore, a vector comprising genes of the human β-defensin 1 and human β-defensin 2 transduced thereinto is used to express the human β-defensin 1 and/or human β-defensin 2 in the oral cavity and suppress the proliferation of causative bacteria of the periodontitis.