FUCOSE SULFATE-CONTEINING POLYSACCHARIDE

PROBLEM TO BE SOLVED: To provide a fucose sulfate-containing polysaccharide that is useful as an apoptosis inducer that can be used as a medicine, a carcinostatic agent and a carcinogenic prophylaxis and provide a method of producing the same. SOLUTION: This fucose sulfate-containing polysaccharide...

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Hauptverfasser: U FUKUKO, KATAYAMA KAORU, SAKAI TAKESHI, KIMURA HITOMI, NAKANISHI YOSHIKUNI, NAKAYAMA SHINJI, KATO IKUNOSHIN, IGAI KATSUSHIGE, SHIMANAKA KAZUO, TOMINAGA TAKAO, KITANO HIDEO, KOJIMA KAORU
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a fucose sulfate-containing polysaccharide that is useful as an apoptosis inducer that can be used as a medicine, a carcinostatic agent and a carcinogenic prophylaxis and provide a method of producing the same. SOLUTION: This fucose sulfate-containing polysaccharide has the following physical and chemical properties: (1) the constituent sugar: includes uronic acid; (2) when this polysaccharide is degraded with the fucoidan-degrading enzyme produced by Flavobacterium sp. SA-0082 (FERM BP-5402), a compound represented by the formula exemplified in the following formula I is formed.