OPTICAL RESOLUTION OF DL-TRYPTOPHANE ESTER

OPTICAL RESOLUTION OF DL-TRYPTOPHANE ESTER

PROBLEM TO BE SOLVED: To provide a method for inexpensively obtaining D-tryptophane or tryptophane derivative that is important as a raw material for medicines by using industrially available (S)-mandelic acid as an optical resolution agent. SOLUTION: In the optical resolution of DL-tryptophane este...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: TAJIMA JUNJI, MIYAMOTO MICHIHIKO, SUZUKI YORIYUKI, SENDA MITSUAKI, FUKUHARA NOBUHIRO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for inexpensively obtaining D-tryptophane or tryptophane derivative that is important as a raw material for medicines by using industrially available (S)-mandelic acid as an optical resolution agent. SOLUTION: In the optical resolution of DL-tryptophane ester into optically active tryptophane or tryptophane derivative, an optically active mandelic acid is used as an optical resolution agent to form their diastereomer and the diastereomer is separated by the fractional crystallization.