MATRIX CONTROL RELEASE DEVICE

PROBLEM TO BE SOLVED: To obtain a controlled release administration composition useful in the administration form for providing controlled release of a medicine having low solubility by a corrosive or diffusing mechanism by making the composition include a specific solid dispersion and a specified c...

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Hauptverfasser:	THOMBRE AVINASH GOVIND, REA ELIZABETH APPEL, CURATOLO WILLIAM JOHN, DWAYNE THOMAS FREESEN, JAMES ALAN SHRIVER NIGHTINGALE
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To obtain a controlled release administration composition useful in the administration form for providing controlled release of a medicine having low solubility by a corrosive or diffusing mechanism by making the composition include a specific solid dispersion and a specified cellulose polymer matrix. SOLUTION: This controlled release administration composition comprises (A) a solid dispersion containing a medicine having a low solubility dispersed into a cellulose polymer in which most of the medicine is amorphous and (B) a water-soluble cellulose polymer matrix mixed with the component A in it. The medicine being a medicine having low solubility means a medicine having