ORALLY ADMINISTRATIVE AGENT FOR TREATING COLITIS

PROBLEM TO BE SOLVED: To obtain the subject orally administrative agent containing a short- chain fatty acid (derivative) as active ingredient and effective for treating colitis caused by antibiotic administration, and also so designed as to be prevented from emitting offensive odor (oxidative rancidity) unique to dose of the short- chain fatty acid and from being absorbed through the stomach and small intestine when orally administered. SOLUTION: This orally administrative agent for treating colitis is obtained by enteric coating of a medicinal mixture containing, as active ingredient, a short-chain fatty acid or derivative thereof such as butyric acid, sodium butyrate or butyrate ester. When needed, prior to the enteric coating, the medicinal mixture is subjected to film-undercoating or, after the enteric coating, the mixture is made into a sugarcoated tablet form or encapsulated.