COLUMN FOR ENTERITIS

PROBLEM TO BE SOLVED: To obtain the subject column capable of performing extracorporeal circulation of blood and improving enteritis by using a polymyxin immobilized carrier. SOLUTION: This column for enteritis is obtained by using a polymyxin immobilized carrier. Preferably, the carrier is a fibrou...

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Bibliographische Detailangaben
Hauptverfasser: HOKARI NAOTO, MURAO YASUO, AYABE TOKIYOSHI, KOUGO YUTAKA, YOKOYAMA AKIRA
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To obtain the subject column capable of performing extracorporeal circulation of blood and improving enteritis by using a polymyxin immobilized carrier. SOLUTION: This column for enteritis is obtained by using a polymyxin immobilized carrier. Preferably, the carrier is a fibrous carrier and its component is a polymer such as a (crosslinked) polystyrene fiber or an acrylic acid.acrylonitrile copolymer fiber and preferably is a sea-island fiber reinforced with the island component. Preferably, a surface area of the carrier is 0.1-100 m2/g. An amount of an immobilized antibiotic substance, polymyxin is pref. >=1 mg/g carrier, further pref. 6-20 mg/g carrier. The column is obtained by mixing the carrier with the polymyxin, and further adding a peptide condensing agent, or the like. By the process, sufficient treatment of inflammable intestinal diseases such as colitis ulcerosa or Crohn's disease can be expected.