PRODUCTION OF 4-(DESDIMETHYLAMINO)TETRACYCLINE

PROBLEM TO BE SOLVED: To provide a method for producing the subject compound having therapeutic applications. SOLUTION: This method for producing 4-(desdimethylamino)tetracycline comprises the following process: tetracycline as raw material is first treated with a methylating agent to form the corre...

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Bibliographische Detailangaben
Hauptverfasser: CARVALHO LUIS, GALINDRO JOSE, SANTOS PEDRO, HEGGIE WILLIAM DR
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for producing the subject compound having therapeutic applications. SOLUTION: This method for producing 4-(desdimethylamino)tetracycline comprises the following process: tetracycline as raw material is first treated with a methylating agent to form the corresponding trimethylammonium salt, which, in turn, is subjected to electrolytic reduction in the presence of an appropriate electrolyte in an aqueous solution at