COMPOSIZIONE FARMACEUTICA DI EMISSIONE REGOLATA PER LA MESSA IN LIBERTA' DI H2-ANTAGONISTI O AGONISTI OD ANTAGONISTI DI SEROTONINA

This invention relates to a controlled release pharmaceutical composition comprising: (a) an outer layer comprising a pH independent hydrophilic polymer together with one or more fillers; and (b) one or more inner layers each comprising an active ingredient; wherein the outer layer is gradually remo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HUCKLE PAUL DERRICK, DANDIKER YOGENDRE
Format: Patent
Sprache:ita
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Beschreibung
Zusammenfassung:This invention relates to a controlled release pharmaceutical composition comprising: (a) an outer layer comprising a pH independent hydrophilic polymer together with one or more fillers; and (b) one or more inner layers each comprising an active ingredient; wherein the outer layer is gradually removed by a combination of dissolution and erosion following administration and the inner layer or layers is gradually removed by a combination of dissolution and erosion or disintegrates rapidly once exposed; and processes for the preparation thereof. In particular the invention relates to pharmaceutical compositions for the controlled release of H2-antagonists or serotonin agonists or antagonists.