IBRIDI FARMACODINAMICI CON ATTIVITA' IPOGLICEMIZZANTE E NO-DONOR OTTENUTI DALLA CONIUGAZIONE DI DERIVATI IDROSSILATI DELLA GLIBENCLAMIDE CON ACIDI CARBOSSILICI NITROOSSI-SOSTITUITI

IBRIDI FARMACODINAMICI CON ATTIVITA' IPOGLICEMIZZANTE E NO-DONOR OTTENUTI DALLA CONIUGAZIONE DI DERIVATI IDROSSILATI DELLA GLIBENCLAMIDE CON ACIDI CARBOSSILICI NITROOSSI-SOSTITUITI

Compound featuring a hypoglycemic action and in the meantime a release of nitric oxide (NO), said compound having the following general formula (I) : where at least one among R, R1, and R2 is a substitute comprising an nitroxy-ester group bound to a acyl aliphatic, aromatic or aliphatic-aromatic gro...

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Bibliographische Detailangaben
Hauptverfasser: MARCHETTI PIERO, TORRI SCILLA, CALDERONE VINCENZO, BALSAMO ALDO, RAPPOSELLI SIMONA
Format: Patent
Sprache:ita
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Zusammenfassung:Compound featuring a hypoglycemic action and in the meantime a release of nitric oxide (NO), said compound having the following general formula (I) : where at least one among R, R1, and R2 is a substitute comprising an nitroxy-ester group bound to a acyl aliphatic, aromatic or aliphatic-aromatic group. The compound can be in particular, used to treat patients affected by NO endogenous deficit responsive to diabetes mellitus of type 2.