DERIVATI OTTICAMENTE ATTIVI DELL ACIDO 5 PENTILAMMINO 5 OXO PENTANOICO R AD ATTIVITA ANTAGONISTA DELLA COLECISTOCHININA E PROCEDIMENTO PER LA LORO PREPARAZIONE

DERIVATI OTTICAMENTE ATTIVI DELL ACIDO 5 PENTILAMMINO 5 OXO PENTANOICO R AD ATTIVITA ANTAGONISTA DELLA COLECISTOCHININA E PROCEDIMENTO PER LA LORO PREPARAZIONE

There are described optically active derivatives of (R) 5-pentylamino-5-oxopentanoic acid and their pharmaceutically acceptable salts, having antagonistic activity towards cholecystokinin, and with the formula: in which R1 is selected from the groups 2-naphthyl, 3,4-dichlorobenzoyl and 3,4-dimethylb...

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Bibliographische Detailangaben
Hauptverfasser: WALTER PERIS, LUIGI ROVATI, FRANCESCO MAKOVEC ROLANDO CHISTE
Format: Patent
Sprache:ita
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:There are described optically active derivatives of (R) 5-pentylamino-5-oxopentanoic acid and their pharmaceutically acceptable salts, having antagonistic activity towards cholecystokinin, and with the formula: in which R1 is selected from the groups 2-naphthyl, 3,4-dichlorobenzoyl and 3,4-dimethylbenzoyl and R2 is a pentyl group or an alkoxyalkyl group with 4 carbon atoms, and in which the substituents on the central chiral group (marked with an asterisk in Formula (I)) have the R (rectus) conformation.