TRIPEPTIDI AD AZIONE IPOTENSIVA EPROCEDIMENTO PR LA LORO SINTESI

Pharmacologically active tripeptides, with at east a retro-inverted peptidic bond, definable by means of the following general formulae:their pharmaceutically acceptable salts, esters or alkyl amides, whereinR, represents a hydrogen atom, an alkyl group with a maximum of 7 carbon atoms, an aryl, hyd...

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Hauptverfasser: GIOVANNISTAZIO, ALESSANDRO SISTO, GIOVANNA DE LUCA, VINCENZO POLITI, ANTONIO SILVIO VERDINI, ANTONINO VIRDIA
Format: Patent
Sprache:ita
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Zusammenfassung:Pharmacologically active tripeptides, with at east a retro-inverted peptidic bond, definable by means of the following general formulae:their pharmaceutically acceptable salts, esters or alkyl amides, whereinR, represents a hydrogen atom, an alkyl group with a maximum of 7 carbon atoms, an aryl, hydroxyai- kyl or hydroxyarylalkyl, guanidylalkyl, amino-alkyl, alkyl oxy-alkyl, acylamino-alkyl, imidazolylalkyl, indolyl-alkyl, mercapto alkyl, alkylmercaptoalkyl, carbamoylalkyl, carboxyalkyl, alkyl-carbamoylalkyl or alkyloxy-carbonylalkyl group;R2 represents agroup,Z is an OH, OR3, NH2, NHR3, group whereinR3 represents an alkyl group with a number of carbon atoms comprised within the range of from 1 to 10.