COMPOSTI ETEROCICLICI CONTENENTI UN GRUPPO C-ACETILE E PROCEDIMENTO PER LA LORO PREPARAZIONE

1-R 2,2-di-(ZOOC-) 3-acetyl 4-oxo-azetidine derivs. of formula (III). Intermediates (IIa) and their tautomers (IIb) are also new. (where R is a protecting gp. or aryl and Z is alkyl). (III) (R is aryl) have anti-hypoxic activity and III (R is a protecting gp.) are intermediates for thienamycin, whic...

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Hauptverfasser:	KAROLY ZAUER, KALMAN HARSANYI, ZSUZSANNA VISKY, GIZELLA BARTA, GYULA SIMIG, GYULA HORNYAK, JOZSEF FETTER, GABOR DOLESCHALL, KAROLY LEMPERT, JOZSEF NYITRAI
Format:	Patent
Sprache:	ita
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	1-R 2,2-di-(ZOOC-) 3-acetyl 4-oxo-azetidine derivs. of formula (III). Intermediates (IIa) and their tautomers (IIb) are also new. (where R is a protecting gp. or aryl and Z is alkyl). (III) (R is aryl) have anti-hypoxic activity and III (R is a protecting gp.) are intermediates for thienamycin, which is a known broad spectrum antibiotic (see US3950357 and DE2751597). Use of (III) allows production of thienamycin in higher yields and by an easier method than known processes. B