DERIVATI DI 5-FLUORO-(BETA-URIDINA OPPURE 2'-DEOSSI-BETA-URIDINA),PROCEDIMENTO PER PRODURLI ED AGENTI CARCINOSTATICI CHE LI CONTENGONO

DERIVATI DI 5-FLUORO-(BETA-URIDINA OPPURE 2'-DEOSSI-BETA-URIDINA),PROCEDIMENTO PER PRODURLI ED AGENTI CARCINOSTATICI CHE LI CONTENGONO

Uridine derivs. of formula (I) (where R1 is acyl; R2 and R3 are opt. protected OH; R4 is H or opt. protected OH) are new. Cpds. (I) are carcinostatic agents with higher activity (against Ehrlich carcinoma and sarcoma (180) and lower toxicity than 5-fluoro-21-desoxy-uridine. Specifically claimed cpds...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: TORU HIRAIWA, MASAHARU OMORI, TOMONOBU YAMAGUCHI, ISAO KITAYAMA, TSUTOMU KODAMA, MASAAKIRA SENOURA, HAJIME AOYAMA, MINAKO YOTSUJI, NOBUO TERASHIMA, YUTAKA KODAMA
Format: Patent
Sprache:ita
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Uridine derivs. of formula (I) (where R1 is acyl; R2 and R3 are opt. protected OH; R4 is H or opt. protected OH) are new. Cpds. (I) are carcinostatic agents with higher activity (against Ehrlich carcinoma and sarcoma (180) and lower toxicity than 5-fluoro-21-desoxy-uridine. Specifically claimed cpds. include 3-p-fluorobenzyl-5-fluoro-21-desoxy-beta-uridine.