DERIVATI DI 5-FLUORO-(BETA-URIDINA OPPURE 2'-DEOSSI-BETA-URIDINA),PROCEDIMENTO PER PRODURLI ED AGENTI CARCINOSTATICI CHE LI CONTENGONO
Uridine derivs. of formula (I) (where R1 is acyl; R2 and R3 are opt. protected OH; R4 is H or opt. protected OH) are new. Cpds. (I) are carcinostatic agents with higher activity (against Ehrlich carcinoma and sarcoma (180) and lower toxicity than 5-fluoro-21-desoxy-uridine. Specifically claimed cpds...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | ita |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Uridine derivs. of formula (I) (where R1 is acyl; R2 and R3 are opt. protected OH; R4 is H or opt. protected OH) are new. Cpds. (I) are carcinostatic agents with higher activity (against Ehrlich carcinoma and sarcoma (180) and lower toxicity than 5-fluoro-21-desoxy-uridine. Specifically claimed cpds. include 3-p-fluorobenzyl-5-fluoro-21-desoxy-beta-uridine. |
---|