Polvere inalabile comprendente voriconazolo in forma cristallina

The present invention relates to a dry powder composition for inhalation use obtained by spray drying, comprising voriconazole, or a pharmaceutically active salt thereof, in substantially crystalline form, in an amount greater than 50% by weight with respect to the total amount of the powder. Said p...

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Bibliographische Detailangaben
Hauptverfasser: Nicosia, Valentina, Faiella, Gianluigi, Caponetti, Giovanni, Magi, Nadia, Castegini, Franco, Zanellotti, Laura, Maggi, Loretta
Format: Patent
Sprache:ita
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Beschreibung
Zusammenfassung:The present invention relates to a dry powder composition for inhalation use obtained by spray drying, comprising voriconazole, or a pharmaceutically active salt thereof, in substantially crystalline form, in an amount greater than 50% by weight with respect to the total amount of the powder. Said powder has a respirable fraction (FPF) greater than 50%, an X90 lower than 6 μm and an MMAD lower than 5 μm.