New substd. vinyl benzodiazepine derivs. and their intermediates useful as anxiolytics - also as antipsychotics and antiaggressives, do not have cataleptic or sedative side effects and have weak anticonvulsive activity

New substd. vinyl benzodiazepine derivs. and their intermediates useful as anxiolytics - also as antipsychotics and antiaggressives, do not have cataleptic or sedative side effects and have weak anticonvulsive activity

1-(2-(Substd. vinyl))-5H-2,3-benzodiazepine derivs. of formula (I) and their acid addn. salts are new. A+B = =C=N or =CH-NH; R1 = Ph (opt. substd. by 2-3 OH or 1-3 halo, CF3, NO2, CN, NH2, mono- or di(1-3C alkyl)amino, 1-4C alkanoylamino, 1-4C alkyl, 1-4C alkoxy, COOH, 1-4C alkoxycarbonyl, 1-4C alko...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: VAGO' PAL, HORVATH KATALIN, SALAMON HASKANE CECILIA, ANDRASI FERENC, BILKEI-GORZO' ANDRAS, BAKONYI ANNA, REITER JOZSEF, GACSALYI ISTVAN, HORVATH EDIT, SZENTKUTI ESZTER, KOROSI JENO, MORAVCSIK IMRE, BLASKO' GABOR, EGYED ANDRAS, GYERTYAN ISTVAN, BOTKA PETER, BERZSENYI PAL, ZOLYOMI GABOR, HAMORI TAMAS, MATE' GYORGYNE
Format: Patent
Sprache:eng ; ita
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:1-(2-(Substd. vinyl))-5H-2,3-benzodiazepine derivs. of formula (I) and their acid addn. salts are new. A+B = =C=N or =CH-NH; R1 = Ph (opt. substd. by 2-3 OH or 1-3 halo, CF3, NO2, CN, NH2, mono- or di(1-3C alkyl)amino, 1-4C alkanoylamino, 1-4C alkyl, 1-4C alkoxy, COOH, 1-4C alkoxycarbonyl, 1-4C alkoxycarbonyloxy or methylenedioxy), or naphthyl (opt. substd. by OH, 1-4C alkoxy or 1-4C acyloxy), or furyl, thienyl or indolyl; R2 = H or 1-4C alkyl; R3, R4 = 1-4C alkoxy attached to positions 7 and 8; or R3 + R4 = 7,8 or 8,9-methylenedioxy.