COMPOSIZIONI FARMACEUTICHE ORALI A PRONTO RILASCIO PER SOSPENSIONI ESTEMPORANEE

The present invention is represented by a prompt-release pharmaceutical composition, suitable in particular for oral use, comprising: a) a plurality of nuclei having dimensions between 50 and 500 mu m, selected among microcrystals of the active ingredient and microgranules containing at least one ac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SANTUS GIANCARLO, GOLZI ROBERTO
Format: Patent
Sprache:ita
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention is represented by a prompt-release pharmaceutical composition, suitable in particular for oral use, comprising: a) a plurality of nuclei having dimensions between 50 and 500 mu m, selected among microcrystals of the active ingredient and microgranules containing at least one active ingredient and at least one pharmaceutically acceptable excipient; b) a lipidic coating comprising a lipidic material sprayed in the melted state onto the said nuclei, and optionally at least one hydrophilic additive; c) a vehicle comprising one or more pharmaceutically acceptable excipients. The coated micronuclei can form a suspension which can be reconstituted by the patient immediately before use by simply adding the suspending phase, or formed into tables or solid aggregates.