Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide
The invention relates to a controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide. This composition, which is vehicled in an appropriate dosage form, comprises a plurality of macrogranules of lipophilic material covered with a mucoadhesive layer. The inv...
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| Format: | Patent |
| Sprache: | eng ; ita |
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| Zusammenfassung: | The invention relates to a controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide. This composition, which is vehicled in an appropriate dosage form, comprises a plurality of macrogranules of lipophilic material covered with a mucoadhesive layer. The invention makes it possible to minimise the diuresis peak and the variability of response which is normally encountered during treatment with this drug.
Oggetto dell'invenzione è una composizione farmaceutica muco-adesiva a rilascio controllato per la somministrazione orale di fuorosemide. Tale composizione, veicolata in opportune forme di dosaggio, consiste in una pluralità di microgranuli di materiale lipofilo ricoperti da uno strato muco-adesivo.L'invenzione permette di minimizzare il picco di diuresi e la variabilità di risposta che normalmente vengono riscontrati durante il trattamento con tale farmaco. |
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