ANTIBIOTICI CEFALOSPORINICI COMPOSIZIONI CHE LI CONTENGONO E PROCEDIMENTI PER PRODURLI

ANTIBIOTICI CEFALOSPORINICI COMPOSIZIONI CHE LI CONTENGONO E PROCEDIMENTI PER PRODURLI

Cephalosporin antibiotics of general formula (I) (wherein Y(+) represents a C-attached 1-C1-4alkylpyridinium group) exhibit broad spectrum antibiotic activity with unusually high activity against strains of Pseudomonas organisms as well as high activity against various members of the Enterobacteriac...

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Bibliographische Detailangaben
Hauptverfasser: BARRY EDWARD AYRES, DAVID GEORGE HUBERT LIVERMORE, CYNTHIA HILDA O CALLAGHAN, NIALL GALBRAITH WEIR, CHRISTOPHER EARLE NEWALL
Format: Patent
Sprache:ita
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Cephalosporin antibiotics of general formula (I) (wherein Y(+) represents a C-attached 1-C1-4alkylpyridinium group) exhibit broad spectrum antibiotic activity with unusually high activity against strains of Pseudomonas organisms as well as high activity against various members of the Enterobacteriaceae. The invention also includes the non-toxic salts, non-toxic metabolically labile esters and 1-oxides of compounds of formula (I). Also described are compositions containing the antibiotics of the invention and processes for the preparation of the antibiotics.