PROCEDIMENTO PER LA PREPARAZIONE DELLA DIOSMINA

Prodn. of diosmine (I) is effected by treating esperidine (II) with iodine in an inert organic solvent and eliminatinq HI with an organic base. - Pref. reaction is effected at between room temp. and 120 deg.C. The solvent is a polar aprotic solvent, esp. DMF, dimethylacetamide or DMSO. The base is p...

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1. Verfasser: VANDONI GUIDO
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Sprache:ita
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Zusammenfassung:Prodn. of diosmine (I) is effected by treating esperidine (II) with iodine in an inert organic solvent and eliminatinq HI with an organic base. - Pref. reaction is effected at between room temp. and 120 deg.C. The solvent is a polar aprotic solvent, esp. DMF, dimethylacetamide or DMSO. The base is pyridine or poly(4-vinylpyridine).