PROCEDIMENTO PER LA PREPARAZIONE DELLA DIOSMINA
Prodn. of diosmine (I) is effected by treating esperidine (II) with iodine in an inert organic solvent and eliminatinq HI with an organic base. - Pref. reaction is effected at between room temp. and 120 deg.C. The solvent is a polar aprotic solvent, esp. DMF, dimethylacetamide or DMSO. The base is p...
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Zusammenfassung: | Prodn. of diosmine (I) is effected by treating esperidine (II) with iodine in an inert organic solvent and eliminatinq HI with an organic base. - Pref. reaction is effected at between room temp. and 120 deg.C. The solvent is a polar aprotic solvent, esp. DMF, dimethylacetamide or DMSO. The base is pyridine or poly(4-vinylpyridine). |
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