COMPOSTO AD ATTIVITA' VASODILATATRICE,ANTIAGGREGANTE E IPOCOLESTEROLEMIZZANTE,PROCEDIMENTO PER LA SUA PREPARAZIONE E COMPOSIZIONE FARMACEUTICHE RELATIVE

COMPOSTO AD ATTIVITA' VASODILATATRICE,ANTIAGGREGANTE E IPOCOLESTEROLEMIZZANTE,PROCEDIMENTO PER LA SUA PREPARAZIONE E COMPOSIZIONE FARMACEUTICHE RELATIVE

The compound having formula (I) (I) is obtained by reacting 1,2-diphenyl-4-[2-phenylsulfinyl)-ethyl]-4-hydroxymethyl-pyrazolidine- 3,5-dione (hydroxymethylsulfinpyrazone) with nicotinic acid, in the presence of activating agents such as DCCD. (I) is endowed with marked vasodilating, antiaggregating...

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1. Verfasser: VANDONI GUIDO
Format: Patent
Sprache:ita
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The compound having formula (I) (I) is obtained by reacting 1,2-diphenyl-4-[2-phenylsulfinyl)-ethyl]-4-hydroxymethyl-pyrazolidine- 3,5-dione (hydroxymethylsulfinpyrazone) with nicotinic acid, in the presence of activating agents such as DCCD. (I) is endowed with marked vasodilating, antiaggregating and hypocholesterolemic properties.