FUROCUMARINA PER LA FOTOCHEMIOTERAPIA DELLA FSORIASI E DI ALTRE MALATTIE CUTANEE AD ESSA SENSIBILI

A class of alkyl-substituted angular flurocoumarins, sometimes termed alkylangelicins, useful in the photochemotherapy of psoriasis and in other skin diseases characterized by cellular hyperproliferation or lack of skin pigmentation is disclosed for topical application or systemic administration. Co...

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Bibliographische Detailangaben
Hauptverfasser:	VEDALDI DANIELA, PASTORINI GIOVANNI, CARLASSARE FRANCESCO, DALL'ACQUA FRANCESCO, RODIGHIERO PAOLO, BACCICHETTI FRANCAROSA, RODIGHIERO GIOVANNI, GUITTO ADRIANO, BORDIN FRANCO
Format:	Patent
Sprache:	ita
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A class of alkyl-substituted angular flurocoumarins, sometimes termed alkylangelicins, useful in the photochemotherapy of psoriasis and in other skin diseases characterized by cellular hyperproliferation or lack of skin pigmentation is disclosed for topical application or systemic administration. Compared with conventional psoralens the described compounds exhibit a lower risk of skin cancer, absence of phototoxicity problems anderithema to the patient so treated. One preferred compound is 5-methylangelicin.