2-metoxýfenýlpíperasín afleiður

2-metoxýfenýlpíperasín afleiður

PCT No. PCT/HU97/00069 Sec. 371 Date Apr. 27, 1999 Sec. 102(e) Date Apr. 27, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/18797 PCT Pub. Date May 7, 1998The invention relates to fused heterocyclic compounds with ring junction nitrogen atom of the formula: wherein Q stands for 2-indolizinyl, 2-imid...

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Hauptverfasser: JUDITH LASZY, GYOERGY FERENCZY, ISTV BETAN LASZLOVSZKY, ESZTER THUROCZYNE K BETALM BETAN, GYOERGY DOM BETANY, EGON K BETARP BETATI, FERENC AUTH, MARGIT PELLIONISZNE PAROCZAI, ID BETAM SARKADI, CSABA SZ BETANTAY JR, S BETANDOR SZABO, BELA HEGEDUS, TIBOR ICS, BELA KISS, ERZSEBET LAPIS, MONIKA CSEJTEI, FERENC TRISCHLER
Format: Patent
Sprache:ice
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PCT No. PCT/HU97/00069 Sec. 371 Date Apr. 27, 1999 Sec. 102(e) Date Apr. 27, 1999 PCT Filed Oct. 22, 1997 PCT Pub. No. WO98/18797 PCT Pub. Date May 7, 1998The invention relates to fused heterocyclic compounds with ring junction nitrogen atom of the formula: wherein Q stands for 2-indolizinyl, 2-imidazo[1,2-a]pyridinyl, 2-imidazo[1,2-a]pyrimidinyl, 6-(2,3-dihydroimidazo[2,1-b]thiazol)-yl or 6-imidazo[2,1-b]thiazolyl group; and n is an integer from 2 to 4, as well as therapeutically useful salts thereof. The invention further relates to pharmaceutical compositions containing these compounds as well as a process for the preparation of the above compounds and compositions. The compounds of formula (I) exhibit mainly antipsychotic effects so the invention relates also to a method of treatment of schizophrenia, organic mental disorders, affective disorders, anxiety and personality disorders.