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Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.

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Bibliographische Detailangaben
Hauptverfasser:	SUSANNAH WILLIAMS, KEVIN DINNELL, PAUL JOSEPH OAKLEY, IAN CHURCHER, ALAN JOHN NADIN, DUNCAN EDWARD SHAW, BRIAN JOHN WILLIAMS, TIMOTHY HARRISON, MARTIN RICHARD TEALL, SONIA KERRAD
Format:	Patent
Sprache:	ice
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.