Nyjar aukaafurthir af guanine

Antivirally active compounds of the formulawherein A isorwherein:m is 1 or 2,n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1,R'a is (CH2)pOH, NHCONH2 or COR"a,R"a is hydrogen, hydroxy or amino,p is 1 to 4,R'b and R" are independently selected from hydrogen or...

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Hauptverfasser: KARL NILS-GUNNAR JOHANSSON, JAN-OLOF NOREN, BJOERN GUNNAR LINDBORG
Format: Patent
Sprache:ice
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Zusammenfassung:Antivirally active compounds of the formulawherein A isorwherein:m is 1 or 2,n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1,R'a is (CH2)pOH, NHCONH2 or COR"a,R"a is hydrogen, hydroxy or amino,p is 1 to 4,R'b and R" are independently selected from hydrogen or (CH2)pOH, with the proviso that at least one of R'b or R"b is hydrogen; orR'b and R"b together constitute an additional carbon-carbon bond to form an alkyne; or a physiologically acceptable salt, geometric or optical isomer thereof; processes for preparation of said compounds, pharmaceutical preparations containing the compounds, methods for treatment of virus infections and the medical use of the compounds.