"MODIFIED FACTOR IX POLYPEPTIDES AND USES THEREOF"

"MODIFIED FACTOR IX POLYPEPTIDES AND USES THEREOF"

The invention relates to modified Factor IX polypeptides such as Factor IX polypeptides with one or more amino acid substitutions. The invention also relates to methods of making modified Factor IX polypeptides, and methods of using modified Factor DC polypeptides, for example, to treat patients aff...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHANDRA PATEL, HEINER APELER, UWE GRITZAN, XIAOQIAO JIANG, ALAN BROOKS, JUN WANG
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention relates to modified Factor IX polypeptides such as Factor IX polypeptides with one or more amino acid substitutions. The invention also relates to methods of making modified Factor IX polypeptides, and methods of using modified Factor DC polypeptides, for example, to treat patients afflicted with hemophilia B.