A NOVEL DISSOLUTION MEDIUM AND A PROCESS FOR ANALYZING THE EFFECT OF ALCOHOL ON DRUG RELEASE AND PERMEATION PATTERN

A NOVEL DISSOLUTION MEDIUM AND A PROCESS FOR ANALYZING THE EFFECT OF ALCOHOL ON DRUG RELEASE AND PERMEATION PATTERN

The present disclosure relates to a novel dissolution medium for analyzing the effect of alcohol on drug release and permeation pattern. The dissolution medium contains alcohol containing fluid and water. The amount of alcohol containing fluid in the dissolution medium of the present disclosure is o...

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Bibliographische Detailangaben
Hauptverfasser: ANAGHA M. JOSHI, , AND, SHIVAJIRAO S. KADAM, ATMARAM P. PAWAR
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to a novel dissolution medium for analyzing the effect of alcohol on drug release and permeation pattern. The dissolution medium contains alcohol containing fluid and water. The amount of alcohol containing fluid in the dissolution medium of the present disclosure is optimized so as to maintain 2.6 wt% of absolute alcohol. The present disclosure also relates to a process for analyzing the effect of co-administration of alcohol or alcoholic beverages on the release and permeation profile of a drug.