SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES

24 12467The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I): wherein Z is CH or N Rand X R R R R R and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GESSIER FRANÇOIS, REN HAIXIA, HERGOVICH LISZTWAN JOANNA, JACOBY EDGAR, KALLEN JOERG, HOLZER PHILIPP, BERGHAUSEN JOERG, FURET PASCAL, PISSOT SOLDERMANN CAROLE, MASUYA KEIICHI, STUTZ STEFAN, BUSCHMANN NICOLE
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	24 12467The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I): wherein Z is CH or N Rand X R R R R R and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4 or variants thereof.