SUBSTANTIALLY PURE STABLE VILAZODONE HYDROCHLORIDE AND A PROCESS THEREOF

SUBSTANTIALLY PURE STABLE VILAZODONE HYDROCHLORIDE AND A PROCESS THEREOF

The present invention is directed to substantially pure stable solid dispersion comprising amorphous Vilazodone Hydrochloride, 5-[4-[4-(5-cyano-lH-indol-3-yl) butyl]-l-piperazinyl]-2- benzofuran carboxamide hydrochloride of formula 1a and a pharmaceutically acceptable water soluble polymer and proce...

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Bibliographische Detailangaben
Hauptverfasser: SINGH, GIRIJ, PAL, SASANE, SACHIN, ARUN, VYAS, RAJESH, VINCHURKAR, ARJUN, NISHIKANT, DESHPANDE, MAHESH, GANPATRAO, BHISE, NANDU, BABAN, PATIL, NITIN, VILAS, THAKARE, DNYANESHWAR, BAPURAO, SHIVDAVKAR, RADHAKRISHNA, BHIKAJI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is directed to substantially pure stable solid dispersion comprising amorphous Vilazodone Hydrochloride, 5-[4-[4-(5-cyano-lH-indol-3-yl) butyl]-l-piperazinyl]-2- benzofuran carboxamide hydrochloride of formula 1a and a pharmaceutically acceptable water soluble polymer and process for preparation thereof.