"INDAZOLE AND PYRAZOLOPYRIDINE COMPOUNDS AS CCRI1 RECEPTOR ANTAGONISTS"

"INDAZOLE AND PYRAZOLOPYRIDINE COMPOUNDS AS CCRI1 RECEPTOR ANTAGONISTS"

Disclosed are CCRI receptor antagonists of the formula (1),wherein X is nitorgen or, C-R.; Ar1 is carbocyele, heteroary or heterocyclyl each optionally substituted by one to three Ra; Ar2 is earboeyele, heteroary or heterocyely, each optionally substituted by one to two R1 is hydrogen, C16 alkyl or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAN MAO, HOSSEIN RAZAVI, BRIAN NICHOLAS COOK, DANIEL KUZMICH
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Disclosed are CCRI receptor antagonists of the formula (1),wherein X is nitorgen or, C-R.; Ar1 is carbocyele, heteroary or heterocyclyl each optionally substituted by one to three Ra; Ar2 is earboeyele, heteroary or heterocyely, each optionally substituted by one to two R1 is hydrogen, C16 alkyl or C1-6 alkoxyC 1-6 alkyl, Also disclosed are compositions, methods of making and using compounds of the formula (1).