PROCESS FOR PREPARING SOLID ORAL MODIFIED-RELEASE COMPOSITION COMPRISING OXCARBAZEPINE OR SALTS THEREOF

PROCESS FOR PREPARING SOLID ORAL MODIFIED-RELEASE COMPOSITION COMPRISING OXCARBAZEPINE OR SALTS THEREOF

The present invention relates to a process for preparing solid oral modified-release composition comprising oxcarbazepine or salts thereof. In particular, the present invention relates to a process for preparing the solid oral modified-release compositions comprising a core of oxcarbazepine or salts...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LALGE, MANOHAR, JAIN, GIRISH KUMAR, KADAM,VINAYAK
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a process for preparing solid oral modified-release composition comprising oxcarbazepine or salts thereof. In particular, the present invention relates to a process for preparing the solid oral modified-release compositions comprising a core of oxcarbazepine or salts thereof coated with a functional coating. Preferably, the composition comprising a core coated with a functional coating comprising one or more rate-controlling excipients having pH-dependent solubility, wherein the core is devoid of excipients having pH dependent solubility. The invention further provides a method of treatment of epileptic seizures.