AN IMPROVED PROCESS FOR THE PREPARATION OF DASATINIB

AN IMPROVED PROCESS FOR THE PREPARATION OF DASATINIB

ABSTRACT The present invention relates to a novel synthetic route to N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl] -2-methyl-4-pyrimidyl] amino]-5-thiazolformamide of the formula I and also relates to the process for the preparation of novel amorphous forms of dasatinib (formu...

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Bibliographische Detailangaben
Hauptverfasser: PATEL, SAMIR, PARMAR, BHUPENDRA, MISTRY, SAMIR, JAYARAMAN, VENKATRAMAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:ABSTRACT The present invention relates to a novel synthetic route to N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl] -2-methyl-4-pyrimidyl] amino]-5-thiazolformamide of the formula I and also relates to the process for the preparation of novel amorphous forms of dasatinib (formula I).