AN ORAL LIQUID FORMULATION AS CYANIDE ANTIDOTE

The invention relates to a novel oral liquid dosage form of Alpha- ketoglutaric acid disodium salt which serves in the treatment of cyanide poisoning. The pharmaceutical formulation is prepared in a flavored sorbitol base to improve the taste, color, stability and bioavailability of the preparation....

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Hauptverfasser: GOPALAN, NATARAJAN, GUJAR, NIRANJAN LAXMAN, RAO, PUTCHA VENKATA LAKSHMANA, SINGH, POONAM, BHATTACHARYA, RAHUL, YADAV, SHIV KUMAR, RAO, POOJA, SINGH, ANIL KUMAR
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creator GOPALAN, NATARAJAN
GUJAR, NIRANJAN LAXMAN
RAO, PUTCHA VENKATA LAKSHMANA
SINGH, POONAM
BHATTACHARYA, RAHUL
YADAV, SHIV KUMAR
RAO, POOJA
SINGH, ANIL KUMAR
description The invention relates to a novel oral liquid dosage form of Alpha- ketoglutaric acid disodium salt which serves in the treatment of cyanide poisoning. The pharmaceutical formulation is prepared in a flavored sorbitol base to improve the taste, color, stability and bioavailability of the preparation. The formulation can also be employed as an energy-rich nutritional supplement or sports medicine to bolster the citric acid cycle or to correct hyperammonemia. The present invention also relates to a process for producing Alpha-ketoglutaric acid disodium salt based pharmaceutical compositions and methods of using such kits for the treatment of cyanide poisoning.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title AN ORAL LIQUID FORMULATION AS CYANIDE ANTIDOTE
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