AN ORAL LIQUID FORMULATION AS CYANIDE ANTIDOTE

The invention relates to a novel oral liquid dosage form of Alpha- ketoglutaric acid disodium salt which serves in the treatment of cyanide poisoning. The pharmaceutical formulation is prepared in a flavored sorbitol base to improve the taste, color, stability and bioavailability of the preparation....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	GOPALAN, NATARAJAN, GUJAR, NIRANJAN LAXMAN, RAO, PUTCHA VENKATA LAKSHMANA, SINGH, POONAM, BHATTACHARYA, RAHUL, YADAV, SHIV KUMAR, RAO, POOJA, SINGH, ANIL KUMAR
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention relates to a novel oral liquid dosage form of Alpha- ketoglutaric acid disodium salt which serves in the treatment of cyanide poisoning. The pharmaceutical formulation is prepared in a flavored sorbitol base to improve the taste, color, stability and bioavailability of the preparation. The formulation can also be employed as an energy-rich nutritional supplement or sports medicine to bolster the citric acid cycle or to correct hyperammonemia. The present invention also relates to a process for producing Alpha-ketoglutaric acid disodium salt based pharmaceutical compositions and methods of using such kits for the treatment of cyanide poisoning.