An Improved Process For Preparing Intermediate of Pranoprofen
The present invention relates to an improved process for preparing intermediate of Pranoprofen, 2-[4-(1-methoxy-1-oxopropan-2-yl)phenoxy]pyridine-3-carboxylic acid of Formula II, by the reaction of methyl-2-(4-hydroxyphenyl)-propionoate with 2-chloronicotinic acid in presence of N-methyl pyrrolidone...
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Zusammenfassung: | The present invention relates to an improved process for preparing intermediate of Pranoprofen, 2-[4-(1-methoxy-1-oxopropan-2-yl)phenoxy]pyridine-3-carboxylic acid of Formula II, by the reaction of methyl-2-(4-hydroxyphenyl)-propionoate with 2-chloronicotinic acid in presence of N-methyl pyrrolidone. |
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