A PROCESS FOR PREPARING EPINEPHRINE INTERMEDIATE

A PROCESS FOR PREPARING EPINEPHRINE INTERMEDIATE

The present invention relates to an in-situ process for DL-Epinephrine from N-benzyl adrenalone, which is finally resolved to provide R-(-)-L-Epinephrine, or an addition salt thereof. Further, it relates to preparation of N-benzyl adrenaline intermediate from N-benzyl adrenalone using readily availa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MERWADE, ARVIND YEKANATHSA, DEO, KESHAV, YADAV, RAMPRASAD, SHINDE, PRAVIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to an in-situ process for DL-Epinephrine from N-benzyl adrenalone, which is finally resolved to provide R-(-)-L-Epinephrine, or an addition salt thereof. Further, it relates to preparation of N-benzyl adrenaline intermediate from N-benzyl adrenalone using readily available, inexpensive and safer reducing reagent, for example, sodium borohydride.