FENOFIBRATE FORMULATION

Various fenofibrate compositions include a plurality of first granules having a high bioavailability in vivo and a plurality of second granules having a low bioavailability in vivo. The first granules may comprise fenofibrate from 0.3% to 10% by weight of the first granules of a first surfactant and...

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Bibliographische Detailangaben
Hauptverfasser:	SHAW ANDREW ALAN, CHATTARAJ SARAT C, REDELMAN GLENN ALLEN
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Various fenofibrate compositions include a plurality of first granules having a high bioavailability in vivo and a plurality of second granules having a low bioavailability in vivo. The first granules may comprise fenofibrate from 0.3% to 10% by weight of the first granules of a first surfactant and a first water soluble or water dispersible cellulose derivative and the second granules may comprise fenofibrate from 0% to 0.25% by weight of the second granules of a second surfactant and a second water soluble or water dispersible cellulose derivative.