Macrocyclic inhibitors of atp citrate lyase

The present disclosure provides, in part, compounds of formula (I), or a stereoisomer and/or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein; pharmaceutical compositions comprising the compounds; and methods of using the compounds to treat conditions, diseases...

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Bibliographische Detailangaben
Hauptverfasser: DAVENPORT Adam James, GLEAVE Laura Jane, PINKOSKY Stephen Lawrence, SOUTHEY Michelle Wing Yan, URSINYOVA Nina Connelly, YARNOLD Christopher John, WALKER Patrick Ross
Format: Patent
Sprache:eng ; heb
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Beschreibung
Zusammenfassung:The present disclosure provides, in part, compounds of formula (I), or a stereoisomer and/or a pharmaceutically acceptable salt thereof, wherein the variables are as defined herein; pharmaceutical compositions comprising the compounds; and methods of using the compounds to treat conditions, diseases, and disorders associated with aberrant levels of lipids.