Ror1-targeted binding molecule and use thereof

The present application relates to an antibody specifically recognizing ROR1, and a preparation method therefor and the use thereof. The present application also relates to an antibody-drug conjugate (ADC) targeting ROR1 and a composition containing the molecule. In addition, the present invention f...

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Hauptverfasser: LANG Guojun, SHU Qingyu, LIU Chanjuan, LIN Chen, XU Peifang, LIU Dongzhou
Format: Patent
Sprache:eng ; heb
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Zusammenfassung:The present application relates to an antibody specifically recognizing ROR1, and a preparation method therefor and the use thereof. The present application also relates to an antibody-drug conjugate (ADC) targeting ROR1 and a composition containing the molecule. In addition, the present invention further relates to the therapeutic and diagnostic uses of the antibodies, antibody fragments and antibody-drug conjugates.