Novel heteroaryl-urea compounds as kv7.2 inhibitors

Novel heteroaryl-urea compounds as kv7.2 inhibitors

The invention provides new heteroaromatic compounds having the general formula (I'), or a solvate or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, Y1, Y2, Y3, and n are as defined herein, compositions including the compounds, processes of manufacturing the compound...

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Bibliographische Detailangaben
Hauptverfasser: NORCROSS Roger David, LI Ronghua, REDONDO PENA Roger Lluis, DAVIDSON James, GERLACH Aaron, SMRCINA Martin, MA Nina, MECHIN Ingrid, GRAHAM Christopher John, DAVIES Nicholas Gareth Morse, CHAPMAN Mark, NAIR Anil, LEBRETON Sylvain, MOWREY David, NAGARAJAN Karthigeyan, SAFAROVA Alena
Format: Patent
Sprache:eng ; heb
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention provides new heteroaromatic compounds having the general formula (I'), or a solvate or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, Y1, Y2, Y3, and n are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.